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Fundamentals of Enzyme Kinetics
(4th edition, 2012)

This page contains information about the book Fundamentals of Enzyme Kinetics 4th edition) by Athel Cornish-Bowden, published by Wiley-Blackwell (2012). Pages related to the 2nd (1995) and 3rd (2004) editions, including reviews and lists of typographical errors, are also still available. There is no intention to update any of these pages in the future.

 Cover design

What’s new in this edition?

  1. The text follows essentially the same pattern as that in the 3rd edition, but is thoroughly revised in detail.
  2. The major additions to the text are concerned with biotechnology and drug development (especially the relationship between enzyme inhibition and drug action).

    Selection of illustrations

  3. The number of illustrations is very greatly increased (about three times as many figures).
  4. Virtually all figures, tables and literature citations now appear on the double-page spread to which they are relevant. In a few cases where this was not possible they are not more than a page away. In particular, references can be found without turning to the back of the book. When the same figure is clearly needed in two places it is shown in both.
  5. Many papers published since 2004 are cited.
  6. Cross-references are shown with actual page numbers (not just section or chapter numbers.)
  7. An increased number of scientists who developed the subjects are now described in marginal notes.

Figures and Sample Chapter

The figures from the book are now available (lightly modified) at the publisher’s site. The files can be found by following the link entitled Supplementary Material, which will activate download of a 150 megabyte ZIP file. They may be freely used for teaching and other non-commercial purposes as long as proper credit is given. Color has been added when appropriate, and additional notes are included. There are also a few figures that are not in the book (mainly variations on the original ones).

At present the figures are available either as Keynote files or as HTML pages (PowerPoint is to be added later). If you have Keynote (2008 or later) installed in your computer the Keynote files are better, but the HTML pages are adequate.

Chapter 1 is available as a PDF file from the same site, as is part of the Index.

Publication data

Fundamentals of Enzyme Kinetics (4th edition) is published by Wiley-Blackwell, Weinheim, Germany. ISBN 978-3-527-33074-4. The book may be obtained from

Previous editions

Principles of Enzyme Kinetics, Butterworths, London, 1976

Fundamentals of Enzyme Kinetics, Butterworths, London, 1979

Fundamentals of Enzyme Kinetics (2nd edition), Portland Press, London, 1995

Fundamentals of Enzyme Kinetics (3rd edition), Portland Press, London, 2004


The only published review that I am aware of (in BAMBED) is linked below. If you notice any that are not listed, please contact me at

Published review

Review at

Review at

List of errors

Most of the errors so far noted are trivial or obvious, and most have been corrected in the second printing (2014). All are listed on another page. If you notice any errors that are not listed, please contact me at