This page contains the abstract of the following article:
M. Hucka, A. Finney, H. M. Sauro, H. Bolouri,
J. C. Doyle, H. Kitano, P. Arkin, B. J. Bornstein, D. Bray,
A. Cornish-Bowden, A. A. Cuellar, S. Dronov, E. D. Gilles,
M. Ginkel, V. Gor, I. I. Goryanin, W. J. Hedley,
T. C. Hodgman, J.-H. Hofmeyr, P. J. Hunter, N. S. Juty,
J. L. Kasberger, A. Kremling, U. Kummer, N. Le Novère,
L. M. Loew, D. Lucio, P. Mendes, E. Minch,
E. D. Mjolsness, Y. Nakayama, M. R. Nelson, P. F. Nielsen,
T. Sakurada, J. C. Schaff, B. E. Shapiro, T. S. Shimizu,
H. D. Spence, J. Stelling, K. Takahashi, M. Tomita,
J. Wagner and J. Wang
(2003) The systems biology markup language (SBML): a
medium for representation and exchange of
biochemical network models
,
Bioinformatics
19, 524–531
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of the complete article is also available.
Motivation: Molecular biotechnology now makes it possible to build elaborate systems models, but the systems biology community needs information standards if models are to be shared, evaluated and developed cooperatively.
Results: We summarize the Systems Biology Markup Language (SBML) Level 1, a free, open, XML-based format for representing biochemical reaction networks. SBML is a software-independent language for describing models common to research in many areas of computational biology, including cell signaling pathways, metabolic pathways, gene regulation, and others.
Availability: The specification of SBML Level 1 is freely available from http://sbml.org/index.psp.