Site map > Home page > M L Cardenas CV

María Luz Cárdenas-Cerda

Full name: María de la Luz Ilze Palmira Antonia Cárdenas-Cerda

This page contains the Curriculum vitæ of María Luz Cárdenas.

1. Identification

Photo Personal History: British citizen. Born in Santiago, Chile; married to Dr. Athel Cornish-Bowden, one daughter.

Present Position: Senior Scientist, CNRS, Marseilles, France

Postal address: Bioénergétique et Ingénierie des Protéines, Centre National de la Recherche Scientifique, 31 chemin Joseph-Aiguier, B.P. 71, 13402 Marseille Cedex 20, France.

Telephone: +33 491 16 41 38 (lab)
Fax: +33 491 16 40 97

Email (MLC): cardenas@imm.cnrs.fr

2. University Education

Undergraduate: University of Chile, Faculty of Chemistry and Pharmacy, School of Biochemistry (1962–1965). Faculty of Sciences, Department of Chemistry (1966–1969). Thesis: Studies on the Interaction between Threonyl-tRNA Synthetase and Threonine tRNA; adviser: Prof. Catherine C. Allende.

Post-graduate: University of Chile, Faculty of Sciences, Post-graduate Program. Thesis: Glucokinase, A Monomeric enzyme with Kinetic Cooperativity; adviser: Prof. Hermann Niemeyer.

3. Academic Degrees

1970 Licenciado en Ciencias with speciality in Chemistry, University of Chile; with Highest Distinction

1982 Doctor en Ciencias with speciality in Biology, University of Chile

4. Honours

Hermann Niemeyer Professor, Facultad de Ciencias, Universidad de Chile, Santiago, Chile, 1993.

2002. Elected corresponding member of the Academia Chilena de Ciencias.

2016. Tito Ureta Prize (Premio Tito Ureta) of the Sociedad de Bioquímica y Biología Molecular de Chile. There is a video showing acceptance in absentia of the prize on the page of images from the Congress of 2016 in Puerto Varas.

5. Field of Research

Biochemistry; Enzymology; Kinetics; Metabolic regulation; Interconvertible enzyme cascades as switches; Mammalian hexokinases; Multi-enzyme systems; Metabolic simulation; Metabolic circularity and the nature of life

6. Scientific Societies

Sociedad de Biología de Chile; Sociedad de Bioquímica y Biología Molecular de Chile; Société Française de Biochimie et de Biologie Moléculaire (France); The Biochemical Society (UK); Sociedad Española de Bioquímica (Spain).

2005–present: Member of the Conseil d’Administration of the Société Française de Biochimie et de Biologie Moléculaire.

7. Positions held

   CHILE

1965–1970

University of Chile, Department of Basic Sciences, School of Veterinary Medicine, Part-time Lecturer and Laboratory Supervisor (in charge of laboratory courses in cell biology and genetics to students of the 1st year of veterinary medicine).

1970–1972

University of Chile, Assistant Professor and Laboratory Supervisor, Department of Basic Sciences, School of Veterinary Medicine (full-time); School of Human Medicine (part-time).

1973–1975

University of Chile, Assistant Professor and Laboratory supervisor, Biology section, School of Human Medicine (full-time).

During the period 1970–1975 my teaching experience included cell biology and genetic couses for students of Medicine (1st year, 25–50 students) and veterinary medicine (1st year, 160–250 students). My teaching responsibility was related especially to the sections of the course concerned with the molecular components of cells and on bioenergetics, and included lectures, demonstrating and examining.

1975–1988

Associate Professor, Section of Biochemistry, Department of Biology, Faculty of Sciences. (During the period 1981 to 1985 the Faculty was fused with the Faculty of Pharmacy under the name of Faculty of Basic Sciences and Pharmacy)

In this period my teaching experience involved participation in undergraduate and postgraduate courses in the area of Biochemistry as mentioned below (Section 7). each course was taught for one semester (i.e. 18 weeks) each year.

   ENGLAND

1982–1985

Honorary Research Fellow, University of Birmingham, Department of Biochemistry. Post-doctoral training in the laboratory of Dr. Ian P. Trayer. Grant-in-Aid from the British Council.

   FRANCE

1987–1988

Maître de Conférences 1ère classe. University of Aix-Marseille II (now Aix-Marseille Université), Faculty of Sciences, Luminy.

1988–2009

Chargé de Recherche 1ère Classe (tenured), Centre National de Recherche Scientifique (CNRS), Marseille.

2009–present

Senior Scientist, Centre National de Recherche Scientifique (CNRS), Marseille.

8. Editorial Board

2004–present

Member of the Editorial Board of the Journal of Biosciences, Bangalore, India

9. International Committee

2011–2012

Member of the 22nd IUBMB and 37th FEBS Advisory Board (Seville, 2012)

10. Thesis Supervision

Maria Lila Vera (1981) Glucose Phosphorylating enzymes of Rat Intestinal Mucosa. Master in enzymology. University of Chile

Alejandro Reyes (1982) Glucose Phosphorylating Isozymes in Hepatocytes and Non-parenchymal Cells Isolated from Rat Liver. Licenciatura degree, Faculty of Basic Sciences and Pharmacy. University of Chile.

Naima Chajri (1991) Molecular Characterisation of glyceraldehyde-3-phosphate dehydrogenase from spinach chloroplasts. Diplome d’Etudes Approfondies d’enzymologie (DEA), Universities of Aix-Marseille II and Paris XI.

Christophe Chevillard (1991) Purification and kinetics studies of glyceraldehyde-3-phosphate dehydrogenase of spinach chloroplasts. Diplome d’Etudes Approfondies d’enzymologie (DEA), Universities of Aix-Marseille II and Paris XI.

11. Publications

Publications from the past ten years are listed here. A complete list is given on a separate page. Invited contributions are indicated by an asterisk (*) next to the name of the person invited.

2020

A. Cornish-Bowden & M. L. Cárdenas (2020) Contrasting Theories of Life: Historical Context, Current Thories. In Search of an Ideal Theory BioSystems 188, 104063 [ DOI link ] 10.1016/j.biosystems.2019.104063

2019

C. Mariscal, A. Barahona, N. Aubert-Kato, A. U. Aydinoglu, S. Bartlett, M. L. Cárdenas, K. Chandru, C. Cleland, B. T. Cocanougher, N. Comfort, A. Cornish-Bowden, T. Deacon, T. Froese, D. Giovannelli, J. Hernlund, P. Hut, J. Kimura, M.-C. Maurel, N. Merino, A. Moreno, M. Nakagawa, J. Peretó, N. Virgo, O. Witkowski, & H. J. Cleaves II Hidden Concepts in the History and Philosophy of Origins-of-Life Studies: A Workshop Report Orig. Life Evol. Biosph. 49, 111 [ DOI link ] 10.1007/s11084-019-09580-x

2018

M. L. Cárdenas, S. Benomar & A. Cornish-Bowden (2018) Rosennean complexity and its relevance to ecology Ecological Complexity 35, 13–24 [Mulitienzyme systems (MLC), Mu48 and Life (AJCB), J23] [ Download PDF ] [ DOI link ] 10.1016/j.ecocom.2017.04.005

2017

A. Cornish-Bowden & M. L. Cárdenas (2017) Life before LUCA J. Theor. Biol. 434, 68–74 [Mulitienzyme systems (MLC), Mu49 and Life (AJCB), J23] [ Download PDF ] [ DOI link ] 10.1016/j.jtbi.2017.05.023

2016

M. L. Cárdenas (2016) Profesor Giorgio Semenza (1928–2016) SEBBM No. 188, 88–49 [ Download PDF ] [Miscellaneous, Mm18]

2015

S. Benomar, D. Ranava, M. L. Cárdenas, E. Trably, Y. Rafrafi, A. Ducret, J. Hamelin, E. Lojou, J.-P. Steyer and M. T. Giudici-Orticon (2015) Nutritional stress induces exchange of cell material and energetic coupling between bacterial species Nat. Comm.6, 6283 [ Download PDF ] [ DOI link ] 10.1038/ncomms7283 Supplementary material

*M. L. Cárdenas (2015) Understanding mechanisms of enzyme cooperativity: the importance of not being at equilibrium Persp. Sci. 4, 10–16 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.12.003

2014

A. Cornish-Bowden, J. Peretó & M. L. Cárdenas (2014) Biochemistry and evolutionary biology: two disciplines that need each other J. Biosci.. 39, 1–15 [ Download PDF ] [ DOI link ] 10.1007/s12038-014-9414-3

J. L. Asenjo, H. C. Ludwig, C. A. Droppelmann, J. G. Cárcamo, I. I. Concha, A. J. Yáñez, M. L. Cárdenas, A. Cornish-Bowden & J. C. Slebe (2014) Subunit interactions in pig-kidney fructose-1,6-bisphosphatase: binding of substrate induces a second class of site with lowered affinity and catalytic activity Biochim. Biophys. Acta 1840, 1798–1807 [ Download PDF ] [ DOI link ] 10.1016/j.bbagen.2013.12.027

*G. Curien, M. L. Cárdenas & A. Cornish-Bowden (2014) Analytical kinetic modelling – a practical procedure in Methods in Molecular Biology (ed. M. Dieuaide-Noubhani & A. P. Alonso) 1090, 261–280

2013

*M. L. Cárdenas (2013) Michaelis and Menten and the long road to the discovery of cooperativity FEBS Lett. 587, 2767–2771 [ Download PDF ] [ DOI link ] 10.1016/j.febslet.2013.07.014

*M. L. Cárdenas & A. Cornish-Bowden (2013) Le centenaire de l'équation de Michaelis et Menten Regard sur la Biochimie, October 2013, 8–9 [ Download PDF ]

*M. L. Cárdenas, G. Piedrafita, *F. Montero & *A. Cornish-Bowden (2013) ¿Qué es la vida? (What is life?) SEBBM No. 175 (March 2013), 14–17 [ Download PDF ]

A. Cornish-Bowden, G. Piedrafita, F. Morán, M. L. Cárdenas & F. Montero (2013) Simulating a model of metabolic closure Biol. Theory 8, 383–390. [ Download PDF ] [ DOI link ] 10.1007/s13752-013-0132-0

2012

*M. L. Cárdenas (2012) Hermann Niemeyer Fernández, a pioneer of Chilean science IUBMB Life 64, 551–555 [ Download PDF ]

M. L. Cárdenas (2012) La biologie synthétique fête son premier centenaire Regard sur la Biochimie, October 2012, 5–6 [ Download PDF ]

2011

*M. L. Cárdenas & A. Cornish-Bowden (2011) Metabolism in Encyclopedia of Astrobioloogy (ed. M. Gargaud) Springer-Verlag, Berlin pp. 1016–1017 [ DOI link ] 10.1007/978-3-642-11274-4

*A. Cornish-Bowden & M. L. Cárdenas (2011) Enzyme in Encyclopedia of Astrobioloogy (ed. M. Gargaud) Springer-Verlag, Berlin pp. 499–500 [ DOI link ] 10.1007/978-3-642-11274-4

*A. Cornish-Bowden, M. L. Cárdenas & E. Lojou (2011) Reflections on energy conversion in biological and biomimetic systems in Functional Nanoscience (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 129–142 [ Download PDF ]

G. Curien, R. Dumas, A. Cornish-Bowden & *M. L. Cárdenas (2011) Different contributions of the various isoenzymes to the flux in the aspartate-derived amino acid pathway in Arabidopsis thaliana in Experimental Standard Conditions of Enzyme Characterizations III (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 107–121 [ Download PDF ]

J.-C. Letelier, M. L. Cárdenas & *A. Cornish-Bowden (2011) From L’Homme Machine to metabolic closure: steps towards understanding life J. Theor. Biol. 286, 100–113 [ Request PDF ] [ DOI link ] 10.1016/j.jtbi.2011.06.033

2010

*M. L. Cárdenas (2010) Prix Nobel de Médecine et Physiologie 2009: les origines d’une découverte peuvent être lointaines Regard sur la Biochimie, April 2010, 3–4 [ Download PDF ]

M. L. Cárdenas, J.-C. Letelier, C. Gutierrez, A. Cornish-Bowden & J. Soto-Andrade (2010) Closure to efficient causation, computability and artificial life J. Theor. Biol. 263, 79–92 [ Request PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2010) Specificity of non-Michaelis–Menten enzymes: necessary information for analyzing metabolic pathways J. Phys. Chem. B 114, 16209–16213 [ Download PDF ]

S. Jaramillo, R. Honorato-Zimmer, U. Pereira, D. Contreras, B. Reynaert, V. Hernández, J. Soto-Andrade, M. L. Cárdenas, A. Cornish-Bowden & J. C. Letelier (2010) (M,R) systems and RAF sets: common ideas, tools and projections Proc. ALIFE XII Conf. (Proceedings of the ALIFE XII Conference, Odense Denmark, August 2010), pp. 94–124 [ Download PDF ]

G. Piedrafita, F. Montero, F. Morán, M. L. Cárdenas & A. Cornish-Bowden (2010) A simple self-maintaining metabolic system: robustness, autocatalysis, bistability PLoS Comp. Biol. 6, e1000872 [ Download PDF ]

12. Books

Cornish-Bowden, A. & Cárdenas, M. L. (eds.) (1990) Control of Metabolic Processes (Proceedings of a NATO Advanced Research Workshop held at Il Ciocco, Italy, 1989), Plenum, New York

*M. L. Cárdenas (1995) Glucokinase: its regulation and role in liver metabolism, R. G. Landes Co, Austin

Cornish-Bowden, A. & Cárdenas, M. L. (eds.) (2000) Technological and Medical Implications of Metabolic Control Analysis (Proceedings of a NATO Advanced Research Workshop held at Visegrád, Hungary, 1999) Kluwer Academic Publishers, Dordrecht, The Netherlands

*A. Cornish-Bowden & *M. L. Cárdenas (2001) Methods 24 (guest editors of an issue on modern methods in kinetics)

13. Invited participation in recent or forthcoming meetings

A list may be found on another page.