This page lists publications of Athel Cornish-Bowden on multienzyme systems other than those concerned mainly with metabolic simulation (1986–present).
H1. A. Cornish-Bowden (1986)
Why is uncompetitive inhibition so rare?
FEBS Lett.
203, 3–6
H2. A. Cornish-Bowden (1987)
Dominance is not inevitable
J. Theor. Biol.
125, 333–338
H3. A. Cornish-Bowden (1987)
The time dimension in steady-state kinetics:
a simplified representation of control coefficients
Biochem. Educ.
15,
144–146
H4. M. L. Cárdenas & A. Cornish-Bowden (1988)
Importance de l’inhibition
incompétitive dans les cascades enzymatiques
(Importance of uncompetitive inhibition in enzyme cascades
)
in
Contrôle du
Métabolisme
(ed. J.-P. Mazat & C. Reder), pp. 43–52,
Bordeaux
(in French)
H5. M. L. Cárdenas & A. Cornish-Bowden (1989)
Characteristics necessary
for an interconvertible enzyme cascade to give a highly sensitive response to
an effector
Biochem. J.
257, 339–345
[Abstract]
H6. A. Cornish-Bowden (1989)
Metabolic control theory and biochemical systems
theory: different objectives, different assumptions, different results
J. Theor. Biol.
136, 365–377
H7. A. Cornish-Bowden (1990)
The nature and role of theory in metabolic control
in
Control of Metabolic Processes
(ed. A. Cornish-Bowden & M. L. Cárdenas) pp. 31–40, Plenum Press, New York
H8. M. L. Cárdenas & A. Cornish-Bowden (1990)
Properties needed for
the enzymes of an interconvertible cascade to generate a highly sensitive response
in
Control of Metabolic Processes
(ed. A. Cornish-Bowden & M. L. Cárdenas) pp. 195–207, Plenum Press, New York
H9. A. Cornish-Bowden & S. E. Szedlacsek (1990)
Very large response coefficients
in interconvertible enzyme cascades
Biomed. Biochim. Acta
49,
829–837
H10. A. Cornish-Bowden (1991)
Failure of channelling to maintain low concentrations
of metabolic intermediates
Eur. J. Biochem.
195, 103–108
H11. J.-H. S. Hofmeyr & A. Cornish-Bowden (1991)
Quantitative assessment
of regulation in metabolic systems
Eur. J. Biochem.
200, 223–236
H12. A. Cornish-Bowden (1991)
How much effect on free metabolite concentrations
does channelling have?
J. Theor. Biol.
152, 39–40
H13. S. E. Szedlacsek, M. L. Cárdenas & A. Cornish-Bowden (1992)
Response
coefficients of interconvertible enzyme cascades towards effectors that act on
one or both modifier enzymes
Eur. J. Biochem.
204, 807–813
H14. J.-H. S. Hofmeyr, A. Cornish-Bowden & J. M. Rohwer (1993)
Taking enzyme
kinetics out of control; putting control into regulation
Eur. J. Biochem.
212, 833–837
H15. A. Cornish-Bowden & M. L. Cárdenas (1993)
Channelling can affect
concentrations of metabolic intermediates at constant net flux: artefact or reality?
Eur. J. Biochem.
213, 87–92
H16. J.-H. S. Hofmeyr & A. Cornish-Bowden (1994)
A control analysis of metabolic
regulation
,
pp. 193–198 in
Modern Trends in Biothermokinetics
(ed. S.
Schuster, M. Rigoulet, R. Ouhabi & J.-P. Mazat), Plenum Press, London
H17. A. Cornish-Bowden, M. L. Cárdenas & J.-H. S. Hofmeyr (1994)
Vers
une meilleure compréhension de la régulation métabolique
Images Rech.
2, 179–182 (in French)
H18. A. Cornish-Bowden (1994)
Kinetic implications of metabolite channelling
in β-oxidation
,
Biochem. Soc. Trans.
22, 451–454
H19. A. Cornish-Bowden (1994)
Théorie du contrôle métabolique
des systèmes biochimiques: considérations sur la nature de la théorie
en biologie
(Theory of metabolic control for biochemical systems: reflections on the nature
of theory in biology
)
pp. 41–49 in La biologie théorique à Solignac
(ed. H. Vérine), Polytechnica,
Paris
(in French)
H20. A. Cornish-Bowden & N. Kellershohn (1994)
Metabolite channelling: does
it allow lower concentrations of intermediates?
pp. 319–323 in
Biothermokinetics
(ed. H. V. Westerhoff), Intercept, Andover
(England)
H21. A. Cornish-Bowden & J.-H. S. Hofmeyr (1994)
Determination of control
coefficients in intact metabolic systems
,
Biochem. J.
298, 367–375
[Abstract]
H22. J.-H. S. Hofmeyr & A. Cornish-Bowden (1994)
How should we quantify metabolic
regulation?
pp. 91–94 in
What is controlling life?
(ed. E. Gnaiger,
F. N. Gellerich & M. Wyss), Innsbruck University Press, Innsbruck
(Austria)
H23. A. Cornish-Bowden (1995)
Metabolic control analysis in theory and practice
Adv. Mol. Cell. Biol.
11, 21–64.
H24. A. Cornish-Bowden (1995)
Kinetics of Multi-Enzyme System
,
in Biotechnology,
a Comprehensive Treatise (2nd edn., ed. H.-J. Rehm & G. Reed), Springer–Verlag,
Weinheim
(Germany),
vol. 9, pp. 121–136
H25. A. Cornish-Bowden (1997)
Kinetic consequences of channelling
in
Channelling
in intermediary metabolism
(ed. L. Agius and H. S. A. Sherratt), Portland
Press, London, pp. 53–70
[Introduction]
H26. A. Cornish-Bowden, J.-H. S. Hofmeyr & M. L. Cárdenas (1995)
Strategies
for manipulating metabolic fluxes in biotechnology
Bioorg. Chem.
23,
439–449
[Abstract]
H27. C. Giersch & A. Cornish-Bowden (1996)
Extending double modulation: combinatorial
rules for identifying the modulations necessary for determining elasticities
in metabolic pathways
,
J. Theor. Biol.
182, 361–369
[Abstract]
H28. J.-H. S. Hofmeyr & A. Cornish-Bowden (1996)
Mathematical description
of regulation in numerical systems: the regulatory potential
,
pp. 3305–3310 in
World
Congress of Nonlinear Analysts ’92
(ed. V. Lakshmikantham), Walter de Gruyter, Berlin
H29. J.-H. S. Hofmeyr & A. Cornish-Bowden (1996)
Co-response analysis: a
new strategy for experimental metabolic control analysis
,
J. Theor. Biol.
182, 371–380
[Abstract]
H30. J.-H. S. Hofmeyr & A. Cornish-Bowden (1996)
Predicting metabolic pathway kinetics with
control analysis
,
pp. 155–158
in BioThermoKinetics
of the Living Cell (ed. H. V.Westerhoff, J. L.Snoep, J. E.Wijker, F. E. Sluse
and B. N. Kholodenko), BioThermoKinetics Press, Amsterdam.
H31. A. Cornish-Bowden (1997)
Vers une meilleure compréhension de
la régulation metabolique
(Towards a better understanding of metabolic regulation
)
pp. 15–25 in
Pharmacocinétique et
biodistribution du médicament. Thérapie génique anti-sens
(ed. J.-M. Lhoste & C. Hélène), Editions
INSERM,
Paris (in French)
[Text in full]
H32. L. Acerenza & A. Cornish-Bowden (1997)
Generalization of the double-modulation
method for in situ determination of elasticities
,
Biochem. J.
327, 217–223
[Abstract and Introduction]
|
[Text in full]
H33. A. Cornish-Bowden (1999)
Metabolic control analysis in biotechnology and medicine
,
Nature Biotechnol.
17, 641–643
[Text in full]
H34. P. de Atauri, R. Curti, J. Puigjaner, A. Cornish-Bowden & M. Cascante (1999)
Advantages and disadvantages of aggregating fluxes into synthetic and degradative fluxes when modelling metabolic pathways
,
Eur. J. Biochem.
265, 671–679
[Abstract]
H35. A. Cornish-Bowden (1999) Enzyme kinetics from a metabolic perspective
Biochem. Soc. Trans.
27, 281–284
[Text in full]
H36. A. Cornish-Bowden & M. L. Cárdenas
(2000)
From genome to cellular phenotype — a role for metabolic flux analysis?
,
Nature Biotechnol.
18, 267–268
[Text in full]
H37. M. L. Cárdenas & A. Cornish-Bowden
(2000)
Metabolic analysis in drug discovery
Science
288, 618–619
[Text in full]
H38. J.-H. S. Hofmeyr & A. Cornish-Bowden
(2000)
Regulating the cellular economy of supply and demand
FEBS Lett.
476, 47–51
[Text in full]
H39. A. Cornish-Bowden & M. L. Cárdenas
(2001)
Silent genes given voice
Nature
409, 571–572
[Text in full]
H40. A. Cornish-Bowden & M. L. Cárdenas
(2001)
Complex networks of interactions connect genes to phenotypes
Trends Biochem. Sci.
26, 463–465
[Text in full]
H41. M. L. Cárdenas & A. Cornish-Bowden
(2001) Haciendo hablar a los genes
Diario de Sevilla,
24
July
2001, pp. 38–39 (in Spanish)
[Text in full]
H42. A. Cornish-Bowden, J.-H. S. Hofmeyr & M. L. Cárdenas
(2002) Stoicheiometric analysis in studies of metabolism
,
Biochem. Soc. Trans. 30, 43–46
[Text in full]
H43. A. Cornish-Bowden & J.-H. S. Hofmeyr
(2002) The role of stoicheiometric analysis in studies of metabolism: an example
,
J. theor. Biol. 216, 179–191
[Acrobat (PDF) file]
H44. M. L. Cárdenas, F. Ortega, M. Cascante & A. Cornish-Bowden (2002)
Modulation of metabolite concentrations
with no net effect on fluxes,
Mol. Biol. Rep. 29, 17–20
[Text in full]
H45. A. Cornish-Bowden & M. L. Cárdenas
(2002) Metabolic balance sheets
,
Nature 420, 129–130
[Text in full
|
PDF file]
H46. A. Cornish-Bowden & M. L. Cárdenas
(2003) Metabolic analysis in drug design
,
C. R. Biologies 326, 509–515
[Abstract
|
PDF file]
H47. A. Cornish-Bowden & J.-H. S. Hofmeyr (2005)
Enzymes in context: kinetic characterization of enzymes for systems biology
The Biochemist 27, 11–14
[Abstract
|
PDF file]
H48 A. Cornish-Bowden & V. Nanjundiah (2006)
The basis of dominance
in
The Biology of Genetic Dominance
(ed. R. A. Veitia)
Landes Bioscience, Georgetown, Texas, pp. 1–16
[Text in full]
H49. A. Cornish-Bowden & M. L. Cárdenas (2007)
Vertical integration from
in
Energy and Protein Metabolism and Nutrition
(ed. I. Ortigues-Marty, N. Miraux & W. Brand-Williams)
Wageningen Academic Publishers, Wageningen,
pp. 463–472
[Text in full]
omics
to the whole organism
H50. E. Meléndez-Hevia, P. de Paz-Lugo, A. Cornish-Bowden & M. L. Cárdenas (2009)
A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis
J. Biosci.
34, 853–872
[PDF file]