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Cornish-Bowden / Cárdenas Publications

This page lists publications of Athel Cornish-Bowden and María Luz Cárdenas, ordered by year of publication, starting with the most recent. Listings by subject area for ACB and MLC may be found on other pages.

Contents

2018

M. L. Cárdenas, S. Benomar & A. Cornish-Bowden (2018) Rosennean complexity and its relevance to ecology Ecological Complexity 35, 13–24 [ Download PDF ] [ DOI link ] 10.1016/j.ecocom.2017.04.005

N. Swainston, A. Baici, B. M. Bakker, A. Cornish-Bowden, P. F. Fitzpatrick, P. Halling, T. S. Leyh, C. O'Donovan, F. M. Raushel, J. M. Rohwer, S. Schnell, D. Schomburg, K. F. Tipton, M.-D. Tsai, H. V. Westerhoff, U. Wittig, R. Wohlgemuth & C. Kettner (2018) STRENDA DB: enabling the validation and sharing of enzyme kinetics data: enabling the validation and sharing of enzyme kinetics data FEBS J. [ Download PDF ] [ DOI link ] 10.1111/febs.14427

2017

A. Cornish-Bowden Overview of the 3rd Conference on Aneuploidy and Cancer in Berkeley, CA USA in 2017 Mol. Cytogen.10 (supplement 2), 77-80 [ Download PDF ] [ DOI link ] 10.1186/s13039-017-0320-x

A. Cornish-Bowden Enthalpy–entropy compensation and the isokinetic temperature in enzyme catalysis J. Biosci. 42, pp. 665–670 [ Download PDF ] [ DOI link ] 10.1007/s12038-017-9719-0

A. Cornish-Bowden & M. L. Cárdenas (2017) Life before LUCA J. Theor. Biol. 434, 68–74 [ Download PDF ] [ DOI link ] 10.1016/j.jtbi.2017.05.023

2016

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A. Bocedi, R. Fabrini, M. Lo Bello, A. M. Caccuri, G. Federici, B. Mannervik, A. Cornish-Bowden & G. Ricci (2016) Evolution of negative cooperativity in glutathione transferase enabled preservation of enzyme function J. Biol. Chem. 292, 26739–26749 [ Download PDF ] [ DOI link ] 10.1074/jbc.M116.749507

M. L. Cárdenas (2016) Profesor Giorgio Semenza (1928–2016) SEBBM No. 188, 88–49 [ Download PDF ]

A. Cornish-Bowden (2016) Biochemical Evolution: the Pursuit of Perfection Garland Science (263 pp.) New York & London

2015

S. Benomar, D. Ranava, M. L. Cárdenas, E. Trably, Y. Rafrafi, A. Ducret, J. Hamelin, E. Lojou, J.-P. Steyer & M. T. Giudici-Orticoni (2015) Nutritional stress induces exchange of cell material and energetic coupling between bacterial species Nat. Comm. 6, 6283 [ Download PDF ] [ DOI link ] 10.1038/ncomms7283 Supplementary material

M. L. Cárdenas (2015) Understanding mechanisms of enzyme cooperativity: the importance of not being at equilibrium Persp. Sci. 4, 10–16 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.12.003

A. Cornish-Bowden (2015) One hundred years of Michaelis–Menten kinetics Persp. Sci. 4, 3–9 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.12.002

A. Cornish-Bowden (2015) Tibor Gánti and Robert Rosen: contrasting approaches to the same problem J. Theor. Biol. 381, 6–10 [ Request PDF ] [ DOI link ] 10.1016/j.jtbi.2015.05.015

A. Cornish-Bowden (2015) Борис Гольдштейн и его вывд уравнений скорости стацонарных реакций [ Download PDF ] (in Russian: translated from "Boris Goldstein and the Derivation of Steady-State Rate Equations" [ Download PDF ] ) pp. 125–138 in Папа: Пущино. Профессия. Палиндромы (ed. L. Lavrova) Nauchniy Mir, Moscow

2014

J. L. Asenjo, H. C. Ludwig, C. A. Droppelmann, J. G. Cárcamo, I. I. Concha, A. J. Yáñez, M. L. Cárdenas, A. Cornish-Bowden & J. C. Slebe (2014) Subunit interactions in pig-kidney fructose-1,6-bisphosphatase: binding of substrate induces a second class of site with lowered affinity and catalytic activity Biochim. Biophys. Acta 1840, 1798–1807 [ Download PDF ] [ DOI link ] 10.1016/j.bbagen.2013.12.027

A. Cornish-Bowden (2014) Understanding allosteric and cooperative interactions in enzymes FEBS J. 281, 621–632 [ Download PDF ] [ DOI link ] 10.1111/febs.12469

A. Cornish-Bowden (2014) Professor Robert Arnold Alberty (1921–2014) The Biochemist 36(3), 57 [ Download PDF ]

A. Cornish-Bowden (2014) Current IUBMB recommendations on enzyme nomenclature and kinetics Persp. Sci. 1, 74–87 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.02.006

A. Cornish-Bowden (2014) Analysis and interpretation of enzyme kinetic data Persp. Sci. 1, 121–125 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.02.010

A. Cornish-Bowden & C. Kettner (2014) Persp. Sci. 1, 1–137 (organizers of a special issue entitled Reporting Enzymology Data — STRENDA Recommendations and Beyond). All of the papers are available at from http://www.sciencedirect.com.

A. Cornish-Bowden, J.-P. Mazat & S. Nicolas (2014) Victor Henri: 111 years of his equation Biochimie 107, 161–166 [ Download PDF ] Supplementary material: Thesis in English; Thesis in French (six parts), Prelims, Introduction, Chapter 1, Chapter 2, Chapter 3, Chapter 4 to end. [ DOI link ] 10.1016/j.biochi.2014.09.018

A. Cornish-Bowden, J. Peretó & M. L. Cárdenas (2014) Biochemistry and evolutionary biology: two disciplines that need each other J. Biosci. 39, 1–15 [ Download PDF ] [ DOI link ] 10.1007/s12038-014-9414-3

G. Curien, M. L. Cárdenas & A. Cornish-Bowden (2014) Analytical kinetic modelling – a practical procedure in Methods in Molecular Biology (ed. M. Dieuaide-Noubhani & A. P. Alonso) 1090, 261–280

U. Deichmann, S. Schuster, J.-P. Mazat & A. Cornish-Bowden (2014) Commemorating the 1913 Michaelis–Menten paper Die Kinetik der Invertinwirkung: three perspectives FEBS J. 281, 435–463 [ Download PDF ] [ DOI link ] 10.1111/febs.12598

C. Kettner & A. Cornish-Bowden (2014) Quo Vadis, enzymology data? Introductory remarks (Introduction to Reporting Enzymology Data — STRENDA Recommendations and Beyond), Persp. Sci. 1, 1–6 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.02.013

K. F. Tipton, R. N. Armstrong, B. M. Bakker, A. Bairoch, A. Cornish-Bowden, P. J. Halling, J.-H. Hofmeyr, T. S. Leyh, C. Kettner, F. M. Raushel, J. Rohwer, D. Schomburg & C. Steinbeck (2014) Standards for reporting enzyme data: the STRENDA consortium: what it aims to do and why it should be helpful Persp. Sci. 1, 131–137 [ Download PDF ] [ DOI link ] 10.1016/j.pisc.2014.02.012

2013

M. L. Cárdenas (2013) Michaelis and Menten and the long road to the discovery of cooperativity FEBS Lett. 587, 2767–2771 [ Download PDF ] [ DOI link ] 10.1016/j.febslet.2013.07.014

M. L. Cárdenas & A. Cornish-Bowden (2013) Le centenaire de l'équation de Michaelis et Menten Regard sur la Biochimie, October 2013, 8–9 [ Download PDF ]

M. L. Cárdenas, G. Piedrafita, F. Montero & A. Cornish-Bowden (2013) ¿Qué es la vida? (What is life?) SEBBM No. 175 (March 2013), 14–17 [ Download PDF ]

A. Cornish-Bowden (2013) The physiological significance of negative cooperativity revisited J. Theor. Biol. 319, 144–147 [ Request PDF ] [ DOI link ] 10.1016/j.jtbi.2012.12.010

A. Cornish-Bowden (2013) The origins of enzyme kinetics FEBS Lett. 587, 2725–2730 [ Download PDF ] [ DOI link ] 10.1016/j.febslet.2013.06.009

A. Cornish-Bowden (2013) Curbing the excesses of low demand Nature 500, 157–158: [ Download PDF ] [ DOI link ] 10.1038/nature12461

A. Cornish-Bowden & J. Lagnado (2013) A woman at the dawn of biochemistry: Maud Leonora Menten The Biochemist 35(6), 46–47 [ Download PDF ]

A. Cornish-Bowden, G. Piedrafita, F. Morán, M. L. Cárdenas & F. Montero (2013) Simulating a model of metabolic closure Biol. Theory 8, 383–390. [ Download PDF ] [ DOI link ] 10.1007/s13752-013-0132-0

2012

M. L. Cárdenas (2012) Hermann Niemeyer Fernández, a pioneer of Chilean science IUBMB Life 64, 551–555 [ Download PDF ] [ DOI link ] 10.1002/iub.1013

 Cover design

A. Cornish-Bowden (2012) Fundamentals of Enzyme Kinetics (4th edn.) Wiley–Blackwell, Weinheim

A. Cornish-Bowden (2012) Enthalpy–entropy compensation as deduced from measurements of temperature dependence in Protein-Ligand Interactions (ed. H. Gohlke) Wiley–Blackwell, Weinheim pp. 33–43 [ Download PDF ]

G. Piedrafita, A. Cornish-Bowden, F. Morán & F. Montero (2012) Size matters: influence of stochasticity on the self-maintenance of a simple model of metabolic closure J. Theor. Biol. 300, 143–151 [ Request PDF ] [ DOI link ] 10.1016/j.jtbi.2012.01.013

G. Piedrafita, K. Ruiz-Mirazo, P.-A. Monnard, A. Cornish-Bowden & F. Montero (2012) Viability conditions for a compartmentalized protometabolic system: a semi-empirical approach PLoS ONE 7, e39480 [ Download PDF ] [ DOI link ] 10.1371/journal.pone.0039480

2011

R. A. Alberty, A. Cornish-Bowden, R. N. Goldberg, G. G. Hammes, K. Tipton & H. V. Westerhoff (2011) Recommendations for terminology and databases for biochemical thermodynamics Biophys. Chem. 155, 89–203 [ Download PDF ] [ DOI link ] 10.1016/j.bpc.2011.03.007

M. L. Cárdenas (2011) L’enseignement de la biochimie au XXIème siècle: Le cycle de Krebs plus jeune que jamais Regard sur la Biochimie, October 2011, 3–4 [ Download PDF ]

M. L. Cárdenas & A. Cornish-Bowden (2011) Metabolism in Encyclopedia of Astrobioloogy (ed. M. Gargaud) Springer-Verlag, Berlin pp. 1016–1017 [ DOI link ] 10.1007/978-3-642-11274-4

A. Cornish-Bowden & M. L. Cárdenas (2011) Enzyme in Encyclopedia of Astrobioloogy (ed. M. Gargaud) Springer-Verlag, Berlin pp. 499–500 [ DOI link ] 10.1007/978-3-642-11274-4

A. Cornish-Bowden, M. L. Cárdenas & E. Lojou (2011) Reflections on energy conversion in biological and biomimetic systems in Functional Nanoscience (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 129–142 [ Download PDF ]

G. Curien, R. Dumas, A. Cornish-Bowden & M. L. Cárdenas (2011) Different contributions of the various isoenzymes to the flux in the aspartate-derived amino acid pathway in Arabidopsis thaliana in Experimental Standard Conditions of Enzyme Characterizations III (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 107–121 [ Download PDF ]

J.-C. Letelier, M. L. Cárdenas & A. Cornish-Bowden (2011) From L’Homme Machine to metabolic closure: steps towards understanding life J. Theor. Biol. 286, 100–113 [ Request PDF ] [ DOI link ] 10.1016/j.jtbi.2011.06.033

2010

R. Apweiler, R. Armstrong, A. Bairoch, A. Cornish-Bowden, P. J. Halling, J.-H. S. Hofmeyr, C. Kettner, T. S. Leyh, J. Rohwer, D. Schomburg, C. Steinbeck & K. Tipton (2010) A large-scale protein-function database Nat. Chem. Biol. 6, 785 [ Download PDF ] . This letter is the subject of an editorial in Nat. Chem. Biol. 6, 783

M. L. Cárdenas (2010) Prix Nobel de Médecine et Physiologie 2009: les origines d’une découverte peuvent être lointaines Regard sur la Biochimie, April 2010, 3–4 [ Download PDF ]

M. L. Cárdenas, J.-C. Letelier, C. Gutierrez, A. Cornish-Bowden & J. Soto-Andrade (2010) Closure to efficient causation, computability and artificial life J. Theor. Biol. 263, 79–92 [ Request PDF ] [ DOI link ] 10.1016/j.jtbi.2009.11.010

A. Cornish-Bowden (2010) Kinetics, Enzymes in The Wiley Encyclopedia of Industrial Biotechnology (ed. A. Seidel), 5, 3047–3060

A. Cornish-Bowden (2010) How I became a biochemist IUBMB Life 62, 84–85 [ Download PDF ] [ DOI link ] 10.1002/iub.265

A. Cornish-Bowden & M. L. Cárdenas (2010) Specificity of non-Michaelis–Menten enzymes: necessary information for analyzing metabolic pathways J. Phys. Chem. B 114, 16209–16213 [ Download PDF ] [ DOI link ] 10.1021/jp106968p

A. Cornish-Bowden, R. N. Goldberg & G. G. Hammes (2010) Professor Robert A. Alberty — a legacy of excellence J. Phys. Chem. B 114, 16045–16046 [ Download PDF ] [ DOI link ] 10.1021/jp105228e

S. Jaramillo, R. Honorato-Zimmer, U. Pereira, D. Contreras, B. Reynaert, V. Hernández, J. Soto-Andrade, M. L. Cárdenas, A. Cornish-Bowden & J. C. Letelier (2010) (M,R) systems and RAF sets: common ideas, tools and projections Proc. ALIFE XII Conf. (Proceedings of the ALIFE XII Conference, Odense Denmark, August 2010), pp. 94–124 [ Download PDF ]

G. Piedrafita, F. Montero, F. Morán, M. L. Cárdenas & A. Cornish-Bowden (2010) A simple self-maintaining metabolic system: robustness, autocatalysis, bistability PLoS Comp. Biol. 6, e1000872 [ Download PDF ]

2009

M. L. Cárdenas (2009) La théorie de l’évolution: plus importante que jamais après 150 ans Regard sur la Biochimie, May 2009, 7–8 [ Download PDF ]

M. L. Cárdenas (2009) ¿Por qué aún cuesta tanto aceptar la teoría de la evolución? Algunas reflexiones (Why so much difficulty for accepting the theory of evolution? Some reflections) SEBBM No. 160 (June 2009), 14–16 [ Download PDF ]

M. L. Cárdenas (2009) Henri-Géry Hers (1923–2008) Regard sur la Biochimie, May 2009, 8–9 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2009) Catalysis at the origin of life viewed in the light of the (M,R) systems of Robert Rosen in Systems Chemistry (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 21–32 [ Download PDF ]

G. Curien, O. Bastien, M. Robert-Genthon, A. Cornish-Bowden, M. L. Cárdenas & R. Dumas (2009) Understanding regulation of aspartate metabolism with a model based on measured kinetic parameters Mol. Syst. Biol. 5, 271 [ Download PDF ] & Supplementary data (PDF file) This paper was selected for the Faculty of 1000 by Lee Sweetlove, who described it as follows: This outstanding paper presents one of the most complete kinetic models of a plant metabolic pathway to date. Focusing on the synthesis of amino acids derived from aspartate, the authors measure a complete set of kinetic parameters for the Arabidopsis enzymes and construct a model that provides significant non-intuitive insight into the control of this pathway...

E. Meléndez-Hevia, P. de Paz-Lugo, A. Cornish-Bowden & M. L. Cárdenas (2009) A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis J. Biosci. 34, 853–872 [ Download PDF ] [ DOI link ] 10.1007/s12038-009-0100-9

2008

A. Cornish-Bowden (2008) Teaching enzyme kinetics and mechanism in the 21st century in Experimental Standard Conditions of Enzyme Characterizations III (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 25–37 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2008) Self-organization at the origin of life J. theor. Biol. 252, 379–387 [ Download PDF ] [ DOI link ] 10.1016/j.jtbi.2007.07.035

A. Cornish-Bowden (2008) Reinhart Heinrich (1946–2006): an annotated bibliography J. Theor. Biol. 252, 379–387 [ Request PDF ]

A. Cornish-Bowden (2008) Jeremy Randall Knowles (1935–2008) The Biochemist 30(3), 46–47 [ Download PDF ]

A. Cornish-Bowden (2008) Monitoring the energy status of a living organism in real time J. Biosci. 33, 629–630 [ Download PDF ]

A. Cornish-Bowden (2008) J. theor. Biol. 252, 377–586 (organizer of a special issue in memory of Reinhart Heinrich)

M. L. Cárdenas (2008) Homenaje al Profesor Gustavo Francisco Hoecker Salas, un pionero de la ciencia chilena. Recuerdos de un maestro An. Acad. Chil. Cienc. 10, 53–63 (in Spanish)

2007

M. Castaing, A. Loiseau & A. Cornish-Bowden (2007) Synergy between verapamil and other multidrug-resistance modulators in model membranes J. Biosci., 32, 737–746 [ Download PDF ]

A. Cornish-Bowden (2007) The IUBMB recommendations on symbolism and terminology in enzyme kinetics in Experimental Standard Conditions of Enzyme Characterizations II (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 27–39 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2007) The threat from creationism to the rational teaching of biology Biol. Res. 40, 113–122

A. Cornish-Bowden & M. L. Cárdenas (2007) La amenaza del creacionismo para la enseñanza racional de la biología (The threat from creationism to the rational teaching of biology) SEBBM No. 153 (September 2007), 8–16 (in Spanish)

A. Cornish-Bowden, M. L. Cárdenas, J.-C. Letelier & J. Soto-Andrade (2007) Beyond reductionism: metabolic circularity as a guiding vision for a real biology of systems Proteomics, 7, 839–845 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2007) Organizational invariance in (M,R) systems Chemistry and Biodiversity, 4, 2396–2406 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2007) Vertical integration from omics to the whole organism in Energy and Protein Metabolism and Nutrition (ed. I. Ortigues-Marty, N. Miraux & W. Brand-Williams) Wageningen Academic Publishers, Wageningen, pp. 463–472 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2007) Bringing chemistry to life: what does it mean to be alive? in Molecular Interactions: Bringing Chemistry to Life (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 27–39 [ Download PDF ]

A. Cornish-Bowden (2007) Interview with Athel Cornish-Bowden Virginia Bioinformatics Institute Newsletter 2, No. 1, p. 4 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2007) The threat from creationism to the rational teaching of biology Biol. Res. 40, 113–122 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2007) La amenaza del creacionismo para la enseñanza racional de la biología (The threat from creationism to the rational teaching of biology) SEBBM No. 153 (September 2007), 8–16 [ Download PDF ]

A. Cornish-Bowden (2007) Reinhart Heinrich (1946–2006) The Biochemist 29(1), 47 [ Download PDF ] reprinted in J. Theor. Biol. 252, 377—378 (2008) [ Request PDF ]

A. Cornish-Bowden (2007) Biochemistry textbooks: are they getting better? The Biochemist 29(5), 16–18 [ Download PDF ]

A. Cornish-Bowden (2007) Daniel E. Koshland, Jr (1920–2007) The Biochemist 29(6), 42–43 [ Download PDF ] M. L. Cárdenas (2007) ¿Quién era Hermann Niemeyer Fernández? (Who was Hermann Niemeyer Fernández?) SEBBM No. 153 (September 2007), 30–32

2006

A. Cornish-Bowden & V. Nanjundiah (2006) The basis of dominance in The Biology of Genetic Dominance (ed. R. A. Veitia) Landes Bioscience, Georgetown, Texas, pp. 1–16 [ Download PDF ]

J.-C. Letelier, J. Soto-Andrade, F. Guíñez Abarzúa, A. Cornish-Bowden & M. L. Cárdenas (2006) Organizational invariance and metabolic closure: analysis in terms of (M,R) systems J. theor. Biol. 238, 949–961 [ Download PDF ]

A. Cornish-Bowden (2006) Putting the Systems back into Systems Biology Persp. Biol. Med. 49, 475–489 [ Download PDF ]

2005

R. Apweiler, A. Cornish-Bowden, J.-H. S. Hofmeyr, C. Kettner, T. S. Leyh, D. Schomburg & K. Tipton (2005) The importance of uniformity in reporting protein-function data Trends Biochem. Sci. 30, 11–12 [ Download PDF ]

G. Chaufan, M. M. Corvi, L. C. San Martín de Viale, M. L. Cárdenas & M. C. Ríos de Molina (2005) Abnormal kinetic behavior of uroporphyrinogen decarboxylase obtained from rats with hexachlorobenzene-induced porphyria J. Biochem. Molec. Toxicol. 19, 19–24 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2005) Handling equilibrium processes embedded in metabolic systems in The Chemical Theatre of Biological Systems (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 185–195 [ Download PDF ]

A. Cornish-Bowden & J.-H. S. Hofmeyr (2005) Enzymes in context: kinetic characterization of enzymes for systems biology The Biochemist 27, 11–14 [ Download PDF ]

A. Cornish-Bowden, M. Jamin & V. Saks (2005) Cinétique enzymatique, EDP Sciences, Paris (in French)

A. Cornish-Bowden (2005) Making systems biology work in the 21st century Genome Biology 6, 317 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2005) Systems biology may work when we learn to understand the parts in terms of the whole Biochem. Soc. Trans. 33, 516–519 [ Download PDF ]

 Cover design

J.-C. Letelier, T. Kuboyama, H. Yasuda, M. L. Cárdenas & A. Cornish-Bowden (2005) A self-referential equation, f(f) = f, obtained using the theory of (M,R) systems: overview and applications in Algebraic Biology 2005 (ed. H. Anai and K. Horimoto) Universal Academy Press, Tokyo, pp. 115–126. [ Download PDF ]

2004

M. L. Cárdenas (2004) Comparative biochemistry of glucokinase in Glucokinase and Glycemic Disease: from Basics to Novel Therapeutics (ed. F. M. Matschinsky & M. A. Magnuson), Karger, Basle, pp. 31–41 [Introduction]

A. Cornish-Bowden (2004) Fundamentals of Enzyme Kinetics (3rd edn.), Portland Press, London (422 pp.)

A. Cornish-Bowden & M. L. Cárdenas (2004) Glucokinase: a monomeric cooperative enzyme with positive cooperativity in Glucokinase and Glycemic Disease: from Basics to Novel Therapeutics (ed. F. M. Matschinsky & M. A. Magnuson), Karger, Basle (Switzerland), pp. 125–134 [Introduction]

A. Cornish-Bowden (2004) The Pursuit of Perfection Oxford University Press, Oxford (170 pp.)

A. Cornish-Bowden, M. L. Cárdenas, J.-C. Letelier, J. Soto-Andrade & F. Guíñez Abarzúa (2004) Understanding the parts in terms of the whole Biol. Cell. 96, 713–717 [ Download PDF ]

J.-C. Letelier, J. Soto-Andrade, F. Guíñez Abarzúa, A. Cornish-Bowden & M. L. Cárdenas, (2004) Metabolic closure in (M,R) systems in Artificial Life IX (ed. J. Pollack, M. Bedau, P. Husbands, T. Ikegami, R. A. Watson) MIT Press, Cambridge, Massachusetts, pp. 255–263. [ Download PDF ]

2003

A. Cornish-Bowden & M. L. Cárdenas (2003) Metabolic analysis in drug design, in Modelling and Simulation of Biological Processes in the Context of Genomics (Proceedings of the Autrans Seminar, ed. P. Amar, F. Képès, V. Norris and P. Traqui), pages 57–65 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2003) Metabolic analysis in drug design, C. R. Biologies 326, 509–515 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2003) Metabolic analysis in drug design: complex, or just complicated? in Molecular Informatics: Confronting Complexity (ed. M. G. Hicks & C. Kettner) Beilstein Institute, Frankfurt, pp. 95–107 [ Download PDF ]

M. Hucka, A. Finney, H. M. Sauro, H. Bolouri, J. C. Doyle, H. Kitano, A. P. Arkin, B. J. Bornstein, D. Bray, A. Cornish-Bowden, A. A. Cuellar, S. Dronov, E. D. Gilles, M. Ginkel, V. Gor, I. I. Goryanin, W. J. Hedley, T. C. Hodgman, J.-H. Hofmeyr, P. J. Hunter, N. S. Juty, J. L. Kasberger, A. Kremling, U. Kummer, N. Le Novère, L. M. Loew, D. Lucio, P. Mendes, E. Minch, E. D. Mjolsness, Y. Nakayama, M. R. Nelson, P. F. Nielsen, T. Sakurada, J. C. Schaff, B. E. Shapiro, T. S. Shimizu, H. D. Spence, J. Stelling, K. Takahashi, M. Tomita, J. Wagner & J. Wang (2003) The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models Bioinformatics 19, 524–531 [ Download PDF ]

O. Monasterio & M. L. Cárdenas (2003) Kinetic studies of rat liver hexokinase D (glucokinase) in non-co-operative conditions show an ordered mechanism with MgADP as the last product to be released Biochem. J. 371, 29–38 [ Download PDF ]

2002

M. L. Cárdenas, F. Ortega, M. Cascante & A. Cornish-Bowden (2002) Modulation of metabolite concentrations with no net effect on fluxes, Mol. Biol. Rep. 29, 17–20 [ Download PDF ]

A. Cornish-Bowden (2002) Statistical analysis of enzyme kinetic data in Enzyme assays (2nd edn., ed. R. Eisenthal & M. J. Danson), Oxford University Press, Oxford, pp. 167–182 [Section titles]

A. Cornish-Bowden, J.-H. S. Hofmeyr & M. L. Cárdenas (2002) Stoicheiometric analysis in studies of metabolism, Biochem. Soc. Trans. 30, 43–46 [ Download PDF ]

A. Cornish-Bowden & J.-H. S. Hofmeyr (2002) The role of stoicheiometric analysis in studies of metabolism: an example, J. theor. Biol. 216, 179–191 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2002) Metabolic balance sheets, Nature 420, 129–130 [ Download PDF ]

A. Cornish-Bowden (2002) Enthalpy–entropy compensation: a phantom phenomenon J. Biosci. 27, 121–126 ; among the 0.2% most cited papers in this journal] [ Download PDF ]

2001

M. L. Cárdenas & A. Cornish-Bowden (2001) Haciendo hablar a los genes Diario de Sevilla, 24 July 2001, pp. 38–39 (in Spanish) [Text in full]

A. Cornish-Bowden (2001) Detection of errors of interpretation in experiments in enzyme kinetics Methods 24, 181–90 [ Download PDF ]

A. Cortés, M. Cascante, M. L. Cárdenas & A. Cornish-Bowden (2001) Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition: new ways of analysing data Biochem. J. 357, 263–268 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2001) Silent genes given voice Nature 409, 571–572 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2001) Complex networks of interactions connect genes to phenotypes Trends Biochem. Sci. 26, 463–465 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2001) Information transfer in metabolic pathways: effects of irreversible steps in computer models, Eur. J. Biochem. 268, 6616–6624 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2001) Methods 24 (guest editors of an issue on modern methods in kinetics) Mk6. M. L. Cárdenas (2001) The competition plot: a kinetic method to assess whether an enzyme that catalyzes multiple reactions does so at a unique site Methods 24, 175–180 [ Download PDF ]

2000

M. L. Cárdenas (2000) Coordination and homeostasis in the response to multiple signals: Role of metabolic cascades, pp. 289–298 in Technological and Medical Implications of Metabolic Control Analysis (ed. A. Cornish-Bowden & M. L. Cárdenas), Kluwer Academic Publishers, Dordrecht, The Netherlands [ Download PDF ]

M. L. Cárdenas & A. Cornish-Bowden (2000) Metabolic analysis in drug discovery Science 288, 618–619 [Text in full]

A. Cornish-Bowden (2000) Steady-state kinetics in Spectrophotometry and Spectrofluorimetry (ed. M. G. Gore), Oxford University Press, Oxford, pp. 167–182

A. Cornish-Bowden & M. L. Cárdenas (2000) From genome to cellular phenotype — a role for metabolic flux analysis?, Nature Biotechnol. 18, 267–268 [ Download PDF ]

A. Cornish-Bowden & R. Eisenthal (2000) Computer simulation as a tool for studying metabolism and drug design, pp. 165–172 in Technological and Medical Implications of Metabolic Control Analysis (ed. A. Cornish-Bowden & M. L. Cárdenas), Kluwer Academic Publishers, Dordrecht, The Netherlands [ Download PDF ]

 Cover design

A. Cornish-Bowden & M. L. Cárdenas (2000) Irreversible Reactions in Metabolic Simulations: how Reversible is Irreversible? in Animating the Cellular Map (ed. J.-H. S. Hofmeyr, J. M. Rohwer & J. L. Snoep) Stellenbosch University Press, Stellenbosch, South Africa, pp. 65–71 [Text in full]

A. Cornish-Bowden (2000) In memoriam: Paul Srere: 1925–1999, pp. 347–349 in Technological and Medical Implications of Metabolic Control Analysis (ed. A. Cornish-Bowden & M. L. Cárdenas), Kluwer Academic Publishers, Dordrecht, The Netherlands [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (2000) Life on earth: probability of a cosmic origin The Biochemist 22(2), 35–38 [Text in full]

A. Cornish-Bowden & M. L. Cárdenas (2000) Technological and Medical Implications of Metabolic Control Analysis (Proceedings of a NATO Advanced Research Workshop held at Visegrád, Hungary, 1999), Kluwer Academic Publishers, Dordrecht, The Netherlands

J.-H. S. Hofmeyr & A. Cornish-Bowden (2000) Regulating the cellular economy of supply and demand FEBS Lett. 476, 47–51 [ Download PDF ]

1999

P. de Atauri, R. Curti, J. Puigjaner, A. Cornish-Bowden & M. Cascante (1999) Advantages and disadvantages of aggregating fluxes into synthetic and degradative fluxes when modelling metabolic pathways, Eur. J. Biochem. 265, 671–679 [ Download PDF ]

 Cover design

A. Cornish-Bowden (1999) Enzyme kinetics from a metabolic perspective, Biochem. Soc. Trans. 27, 281–284 [ Download PDF ]

A. Cornish-Bowden (1999) Kinetics, Enzymes in The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis and Bioseparation (ed. M. C. Flickinger & S. Drew), pp. 1505–1512

A. Cornish-Bowden (1999) Metabolic control analysis in biotechnology and medicine, Nature Biotechnol. 17, 641–643 [ Download PDF ]

A. Cornish-Bowden (1999) Basic Mathematics for Biochemists (2nd edn.), Oxford University Press, Oxford (225 pp.)

A. Cornish-Bowden (1999) The origins of enzymology The Biochemist 19(2), 36–38 [Text in full]

A. Cornish-Bowden (1999) Metabolic complexity has no bearing on genetic determinism Behav. Brain Sc. 22, 889–890 (Target article and all of the reviews) [ Download PDF ]

1998

M. L. Cárdenas, A. Cornish-Bowden & T. Ureta (1998) Evolution and regulatory role of the hexokinases Biochim. Biophys. Acta 1401, 242–264 [ Download PDF ]

A. Cornish-Bowden (1998) Two centuries of catalysis J. Biosci. 23, 87–92 [ Download PDF ]

R. Eisenthal & A. Cornish-Bowden (1998) Prospects for antiparasitic drugs: the case of Trypanosoma brucei, the causative agent of African sleeping sickness, J. Biol. Chem. 273, 5500–5505 [ Download PDF ]

1997

L. Acerenza & A. Cornish-Bowden (1997) Generalization of the double-modulation method for in situ determination of elasticities, Biochem. J. 327, 217–223 [ Download PDF ]

M. L. Cárdenas (1997) Kinetic behaviour of vertebrate hexokinases with emphasis on hexokinase D (IV) Biochem. Soc. Trans. 25, 131–135 [ Download PDF ]

M. L. Cárdenas (1997) Problèmes de l’enzymologie actuelle pp. 27–44 in Pharmacocinétique et biodistribution du médicament. Thérapie génique anti-sens (ed. J.-M. Lhoste & C. Hélène), Editions INSERM, Paris (in French)

M. L. Cárdenas (1997) Metabolic cascades: an evolutionary strategy for an integrated and sensitive response to multiple signals, pp. 159–172 in New Beer in an Old Bottle: Eduard Buchner and the Growth of Biochemical Knowledge (ed. A. Cornish-Bowden), Universitat de València, Valencia, Spain [ Download PDF ]

A. Cornish-Bowden (1997) Harden and Young’s discovery of fructose 1,6-bisphosphate, pp. 135–148 in New Beer in an Old Bottle: Eduard Buchner and the Growth of Biochemical Knowledge (ed. A. Cornish-Bowden), Universitat de València, Valencia, Spain [ Download PDF ]

A. Cornish-Bowden (1997) Kinetic consequences of channelling in Channelling in intermediary metabolism (ed. L. Agius and H. S. A. Sherratt), Portland Press, London, pp. 53–70

A. Cornish-Bowden (1997) Vers une meilleure compréhension de la régulation metabolique (Towards a better understanding of metabolic regulation) pp. 15–25 in Pharmacocinétique et biodistribution du médicament. Thérapie génique anti-sens (ed. J.-M. Lhoste & C. Hélène), Editions INSERM, Paris (in French) [Text in full]

 Cover design

A. Cornish-Bowden (1997) New Beer in an Old Bottle: Eduard Buchner and the Growth of Biochemical Knowledge Universitat de València, Valencia, Spain

A. Cornish-Bowden & R. Eisenthal (1997) Prospects for pharmacological manipulation of metabolism, pp. 215–224 in New Beer in an Old Bottle: Eduard Buchner and the Growth of Biochemical Knowledge (ed. A. Cornish-Bowden), Universitat de València, Valencia, Spain [ Download PDF ]

R. Giordani, J. Buc, A. Cornish-Bowden & M. L. Cárdenas (1997) Kinetics of membrane-bound nitrate reductase A from Escherichia coli with analogues of physiological electron donors: different reaction sites for menadiol and duroquinol Eur. J. Biochem. 250, 567–577 [ Download PDF ]

J.-H. S. Hofmeyr & A. Cornish-Bowden (1997) The reversible Hill equation: How to incorporate cooperative enzymes into metabolic models Comp. Appl. Biosci. 13, 377–385 [ Download PDF ]

K. J. Laidler & A. Cornish-Bowden (1997) Elizabeth Fulhame and the discovery of catalysis: 100 years before Buchner, pp. 123–126 in New Beer in an Old Bottle: Eduard Buchner and the Growth of Biochemical Knowledge (ed. A. Cornish-Bowden), Universitat de València, Valencia, Spain [ Download PDF ]

1996

M. L. Cárdenas & A. Goldbeter (1996) The glucose-induced switch between glycogen phosphorylase and glycogen synthase in the liver: outlines of a theoretical approach J. Theor. Biol. 182, 421–426 [ Download PDF ]

A. Cornish-Bowden (1996) Henrik Kacser (1918–1995): an annotated bibliography J. Theor. Biol. 182, 195–199 [ Download PDF ]

A. Cornish-Bowden (1996) J. theor. Biol. 182, 193-457 (organizer of a special issue in memory of Henrik Kacser)

C. Giersch & A. Cornish-Bowden (1996) Extending double modulation: combinatorial rules for identifying the modulations necessary for determining elasticities in metabolic pathways, J. Theor. Biol. 182, 361–369 [ Download PDF ]

R. Giordani, M. L. Cárdenas, J. Moulin-Traffort & P. Regli (1996) Fungicidal activity of latex sap from Carica papaya and antifungicidal effect of D(+)-glucosamine on Candida albicans growth Mycoses 39, 103–110 [ Download PDF ]

J.-H. S. Hofmeyr & A. Cornish-Bowden (1996) Co-response analysis: a new strategy for experimental metabolic control analysis, J. Theor. Biol. 182, 371–380 [ Download PDF ]

J.-H. S. Hofmeyr & A. Cornish-Bowden (1996) Mathematical description of regulation in numerical systems: the regulatory potential, pp. 3305–3310 in World Congress of Nonlinear Analysts ’92 (ed. V. Lakshmikantham), Walter de Gruyter, Berlin

J.-H. S. Hofmeyr & A. Cornish-Bowden (1996) Predicting metabolic pathway kinetics with control analysis, pp. 155–158 in BioThermoKinetics of the Living Cell (ed. H. V.Westerhoff, J. L.Snoep, J. E.Wijker, F. E. Sluse and B. N. Kholodenko), BioThermoKinetics Press, Amsterdam.

1995

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J. Buc, C.-L. Santini, F. Blasco, R. Giordani, M. L. Cárdenas, M. Chippaux, A. Cornish-Bowden & G. Giordano (1995) Kinetic studies of a soluble α–β nitrate reductase from Escherichia coli: use of various α–β mutants with altered β subunits Eur. J. Biochem. 234, 766–772 [ Download PDF ]

M. L. Cárdenas (1995) Glucokinase: its regulation and role in liver metabolism, R. G. Landes Co, Austin

A. Cornish-Bowden (1995) Analysis of Enzyme Kinetic Data, Oxford University Press, Oxford (198 pp.)

A. Cornish-Bowden (1995) Fundamentals of Enzyme Kinetics (2nd edn.), Portland Press, London (343 pp.)

A. Cornish-Bowden (1995) Classification and measurement of enzyme activity in Enzymology Labfax (ed. P. Engel), pp. 1–7, Bios, Oxford

A. Cornish-Bowden (1995) Plotting methods in Enzymology Labfax (ed. P. Engel), pp. 96–113, Bios, Oxford

A. Cornish-Bowden (1995) Metabolic control analysis in theory and practice Adv. Mol. Cell. Biol. 11, 21–64. [ Download PDF ]

A. Cornish-Bowden (1995) Kinetics of Multi-Enzyme Systems, in Biotechnology, a Comprehensive Treatise (2nd edn., ed. H.-J. Rehm & G. Reed), Springer–Verlag, Weinheim (Germany), vol. 9, pp. 121–136

A. Cornish-Bowden, J.-H. S. Hofmeyr & M. L. Cárdenas (1995) Strategies for manipulating metabolic fluxes in biotechnology Bioorg. Chem. 23, 439–449 [ Download PDF ]

1994

A. Cornish-Bowden (1994) Product inhibition in mechanisms in which the free enzyme isomerizes Biochem. J. 301, 621–623 [ Download PDF ]

A. Cornish-Bowden (1994) Kinetic implications of metabolite channelling in β-oxidation, Biochem. Soc. Trans. 22, 451–454 [ Download PDF ]

A. Cornish-Bowden (1994) Théorie du contrôle métabolique des systèmes biochimiques: considérations sur la nature de la théorie en biologie (Theory of metabolic control for biochemical systems: reflections on the nature of theory in biology) pp. 41–49 in La biologie théorique à Solignac (ed. H. Vérine), Polytechnica, Paris (in French)

A. Cornish-Bowden, M. L. Cárdenas & J.-H. S. Hofmeyr (1994) Vers une meilleure compréhension de la régulation métabolique Images Rech.

A. Cornish-Bowden & J.-H. S. Hofmeyr (1994) Determination of control coefficients in intact metabolic systems, Biochem. J. 298, 367–375 [ Download PDF ]

A. Cornish-Bowden & N. Kellershohn (1994) Metabolite channelling: does it allow lower concentrations of intermediates? pp. 319–323 in Biothermokinetics (ed. H. V. Westerhoff), Intercept, Andover (England)

J.-H. S. Hofmeyr & A. Cornish-Bowden (1994) A control analysis of metabolic regulation, pp. 193–198 in Modern Trends in Biothermokinetics (ed. S. Schuster, M. Rigoulet, R. Ouhabi & J.-P. Mazat), Plenum Press, London

J.-H. S. Hofmeyr & A. Cornish-Bowden (1994) How should we quantify metabolic regulation? pp. 91–94 in What is controlling life? (ed. E. Gnaiger, F. N. Gellerich & M. Wyss), Innsbruck University Press, Innsbruck (Austria)

1993

R. A. Alberty & A. Cornish-Bowden (1993) The pH dependence of the apparent equilibrium constant, K′, of a biochemical reaction Trends Biochem. Sci. 18, 288–289 [ Download PDF ]

M. L. Cárdenas (1993) Una tesis con Hermann Niemeyer: un pretexto para expresar mis sentimientos Arch. Biol. Med. Exp.25, 109–114 (in Spanish)

M. L. Cárdenas & D. Aragnol (1993) High sensitivity to effectors in metabolic cascades: amodel for okadaic acid effects pp. 51–57 in Biothermokinetics (ed. H. V. Westerhoff), Intercept, Andover

M. L. Cárdenas & A. Cornish-Bowden (1993) Rounding error: an unexpected fault in the output from a recording spectrophotometer Biochem. J. 292, 37–40 [ Download PDF ]

C. Chevillard, M. L. Cárdenas & A. Cornish-Bowden (1993) The competition plot: a simple test of whether two reactions occur at the same active site Biochem. J. 289, 599–604 [ Download PDF ]

A. Cornish-Bowden (1993) Enzyme specificity in reactions of more than one co-substrate Biochem. J. 291, 323–324 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (1993) Channelling can affect concentrations of metabolic intermediates at constant net flux: artefact or reality? Eur. J. Biochem. 213, 87–92 [ Download PDF ]

J.-H. S. Hofmeyr, A. Cornish-Bowden & J. M. Rohwer (1993) Taking enzyme kinetics out of control; putting control into regulation Eur. J. Biochem. 212, 833–837 [ Download PDF ]

1992

A. Cornish-Bowden (1992) Las hexoquinasas de mamíferos en la regulación metabólica (Mammalian hexokinases in metabolic regulation) Arch. Biol. Med. Exper. 25, 133–137 (in Spanish)

S. E. Szedlacsek, M. L. Cárdenas & A. Cornish-Bowden (1992) Response coefficients of interconvertible enzyme cascades towards effectors that act on one or both modifier enzymes Eur. J. Biochem. 204, 807–813 [ Download PDF ]

1991

M. L. Cárdenas (1991) Are the transitory enzyme–enzyme complexes found in vitro also transitory in vivo? If so, are they physiologically important? J. Theor. Biol. 152, 113-115. [ Download PDF ]

A. Cornish-Bowden (1991) Parameter estimating procedures for the Michaelis–Menten model: reply to Tseng and Hsu J. Theor. Biol. 153, 437–440 [ Download PDF ]

A. Cornish-Bowden (1991) Failure of channelling to maintain low concentrations of metabolic intermediates Eur. J. Biochem. 195, 103–108 [ Download PDF ]

A. Cornish-Bowden (1991) How much effect on free metabolite concentrations does channelling have? J. Theor. Biol. 152, 39–40 [ Download PDF ]

A. Cornish-Bowden (1991) J. theor. Biol. 152, 1-141 (organizer of a special issue devoted to metabolite channelling)

A. Cornish-Bowden & M. L. Cárdenas (1991) Hexokinase and glucokinase in liver metabolism Trends Biochem. Sci. 16, 281–282. Additional correspondence in vol. 17, p. 59. [ Download PDF ]

A. Cornish-Bowden & J.-H. S. Hofmeyr (1991) MetaModel: a program for modelling and control analysis of metabolic pathways on the IBM PC and compatibles Comp. Appl. Biosci. 7, 89–93 [ Download PDF ]

J.-H. S. Hofmeyr & A. Cornish-Bowden (1991) Quantitative assessment of regulation in metabolic systems Eur. J. Biochem. 200, 223–236 [ Download PDF ]

1990

M. L. Cárdenas & A. Cornish-Bowden (1990) Properties needed for the enzymes of an interconvertible cascade to generate a highly sensitive response in Control of Metabolic Processes (ed. A. Cornish-Bowden & M. L. Cárdenas) pp. 195–207, Plenum Press, New York [ Download PDF ] <p>A. Cornish-Bowden (1990) The nature and role of theory in metabolic control in Control of Metabolic Processes (ed. A. Cornish-Bowden & M. L. Cárdenas) pp. 31–40, Plenum Press, New York [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (1990) Control of Metabolic Processes (Proceedings of a NATO Advanced Research Workshop held at Il Ciocco, Italy, 1989), Plenum Press, New York p>A. Cornish-Bowden & S. E. Szedlacsek (1990) Very large response coefficients in interconvertible enzyme cascades Biomed. Biochim. Acta 49, 829–837 [ Download PDF ]

1989

M. L. Cárdenas & A. Cornish-Bowden (1989) Characteristics necessary for an interconvertible enzyme cascade to give a highly sensitive response to an effector Biochem. J. 257, 339–345 [ Download PDF ]

A. Cornish-Bowden (1989) Non-equilibrium isotope-exchange methods for investigating enzyme mechanisms Curr. Topics Cell. Reg. 30, 143–169 [ Download PDF ]

A. Cornish-Bowden (1989) Uso de resonancia magnética nuclear de 31P y [γ-(S)-16O, 17O, 18O]ATP quiral para investigar los cursos estereoquímicos de las reacciones catalizadas por enzimas (Use of 31P-NMR and chiral [γ-(S)-16O, 17O, 18O]ATP to investigate the stereochemical courses of enzyme-catalysed reactions) Arch. Biol. Med. Exper. 22, 139–146 (in Spanish) [ Download PDF ]

A. Cornish-Bowden (1989) Metabolic control theory and biochemical systems theory: different objectives, different assumptions, different results J. Theor. Biol. 136, 365–377 [ Download PDF ]

A. Cornish-Bowden (1989) Uso de resonancia magnética nuclear de 31P y [γ-(S)-16O, 17O, 18O]ATP quiral para investigar los cursos estereoquímicos de las reacciones catalizadas por enzimas (Use of 31P-NMR and chiral [γ-(S)-16O, 17O, 18O]ATP to investigate the stereochemical courses of enzyme-catalysed reactions) Arch. Biol. Med. Exper. 22, 139–146 (in Spanish)

B. Gontero, M. L. Cárdenas & J. Ricard (1988) A functional five-enzyme complex of chloroplasts involved in the Calvin cycle Eur. J. Biochem. 173, 437–443 [ Download PDF ]

1988

M. L. Cárdenas & A. Cornish-Bowden (1988) Importance de l’inhibition incompétitive dans les cascades enzymatiques (Importance of uncompetitive inhibition in enzyme cascades) in Contrôle du Métabolisme (ed. J.-P. Mazat & C. Reder), pp. 43–52, Bordeaux (in French)

A. Cornish-Bowden (1988) Saturation functions as a nested set J. Theor. Biol. 130, 125–126 [ Download PDF ]

A. Cornish-Bowden (1988) Abrupt transitions in kinetic plots: an artifact of plotting procedures Biochem. J. 250, 309–311 [ Download PDF ]

A. Cornish-Bowden (1988) Convergent evolution of lysozyme sequences? Nature 332, 787–788 [ Download PDF ]

A. Cornish-Bowden (1988) Significance of the purine–pyrimidine motif present in most gene groups J. Theor. Biol. 134, 1–7 [ Download PDF ]

A. Cornish-Bowden (1988) Significance of the purine–pyrimidine motif present in most gene groups J. Theor. Biol. 134, 1–7

A. Cornish-Bowden & C. W. Wharton (1988) Enzyme Kinetics, IRL Press, Oxford (77 pp.)

1987

A. Cornish-Bowden (1987) Dominance is not inevitable J. Theor. Biol. 125, 333–338 [ Download PDF ]

A. Cornish-Bowden (1987) The time dimension in steady-state kinetics: a simplified representation of control coefficients Biochem. Educ. 15, 144–146 [ Download PDF ]

A. Cornish-Bowden & M. L. Cárdenas (1987) Fundamentals: chemistry of enzymes in Biotechnology: a Comprehensive Treatise (ed. J. F. Kennedy), vol. 7a, pp. 3–33, Verlag Chemie, Weinheim (Germany),

A. Cornish-Bowden & M. L. Cárdenas (1987) Co-operativity in monomeric enzymes J. Theor. Biol. 124, 1–23 [ Download PDF ]

D. Pollard-Knight & A. Cornish-Bowden (1987) Kinetics of hexokinase D (glucokinase) with inosine triphosphate as phosphate donor Biochem. J. 245, 625–629 [ Download PDF ]

J. Ricard & A. Cornish-Bowden (1987) Co-operative and allosteric enzymes: 20 years on Eur. J. Biochem. 166, 255–272 [ Download PDF ]

1986

K. Asem, A. J. Cornish-Bowden & J. A. Cole (1986) A comparative study of the extracellular glucosyl- and fructosyltransferases from cariogenic and non-cariogenic Streptococcus mutans strains of two different serotypes Microbios 47, 53–66 [ Download PDF ]

B. Bezeau, M. J. Clements, A. Cornish-Bowden, L. Endrenyi & J. Wang (1986) Design and analysis of enzyme kinetic experiments. Efficiency and robustness of the parameters in Dynamics of Biochemical Systems (ed. T. Keleti, S. Damjanovich & L. Trón), pp. 289–308, Akadémiai Kiadó, Budapest [ Download PDF ]

M. L. Cárdenas, E. Rabajille, I. P. Trayer & H. Niemeyer (1985)Cooperative interactions in hexokinase D (glucokinase). Kinetic and fluorescence studies Arch. Biol. Med. Exp. 18, 273–284

A. Cornish-Bowden (1986) Why is uncompetitive inhibition so rare? FEBS Lett. 203, 3–6 [ Download PDF ]

A. Cornish-Bowden (1986) Why are enzymes so small?, or, why do biochemists ask why are enzymes so big?? Trends Biochem. Sci. 11, 286 [ Download PDF ]

A. Cornish-Bowden & L. Endrenyi (1986) Robust regression of enzyme kinetic data Biochem. J. 234, 21–29 [ Download PDF ]

A. Cornish-Bowden & L. Endrenyi (1986) Estimation of enzyme kinetic parameters without prior information about weights or error distribution in Dynamics of Biochemical Systems (ed. T. Keleti, S. Damjanovich & L. Trón), pp. 309–322, Akadémiai Kiadó, Budapest [ Download PDF ]

A. Cornish-Bowden & A. C. Storer (1986) Mechanistic origin of the sigmoidal rate behaviour of rat liver hexokinase D (glucokinase) Biochem. J. 240, 293–296 [ Download PDF ]

M. Gregoriou, I. P. Trayer & A. Cornish-Bowden (1986) Allosteric character of the inhibition of rat-muscle hexokinase B by glucose 6-phosphate Eur. J. Biochem. 161, 171–176 [ Download PDF ]

1985

J. A. Burns, A. Cornish-Bowden, A. K. Groen, R. Heinrich, H. Kacser, J. W. Porteous, S. M. Rapoport, T. A. Rapoport, J. W. Stucki, J. M. Tager, R. J. A. Wanders and H. V. Westerhoff (1985) Control analysis of metabolic systems Trends Biochem. Sci. 10, 16 [ Download PDF ]

M. L. Cárdenas, E. Rabajille, I. P. Trayer & H. Niemeyer (1985)Cooperative interactions in hexokinase D (glucokinase). Kinetic and fluorescence studies Arch. Biol. Med. Exp. 18, 273–284

A. Cornish-Bowden (1985) A FORTRAN program for robust regression of enzyme kinetic data in Techniques in Protein and Enzyme Biochemistry (ed. K. F. Tipton), Elsevier, Amsterdam, BS115, pp. 1–22

A. Cornish-Bowden (1985) Enzyme kinetics in Comprehensive Biotechnology (ed. M. Moo-Young), vol. 1, pp. 521–538, Pergamon, Oxford

A. Cornish-Bowden (1985) Are introns structural elements or evolutionary debris? Nature 313, 434–435 [ Download PDF ]

A. Cornish-Bowden (1985) The amino acid sequences of the copper/zinc superoxide dismutases from swordfish and Photobacter leiognathi confirm the predictions made from the compositions Eur. J. Biochem. 151, 333–335 [ Download PDF ]

A. Cornish-Bowden & D. Pollard-Knight (1985) Solvent isotope effects on the hexokinase IV reaction: evidence for the mnemonical interpretation of the kinetic co-operativity Arch. Biol. Med. Exper. 18, 293–300 [ Download PDF ]

H. Niemeyer & M. L. Cárdenas (1985) Concurrencia de mecanismos múltiples e integrados en la modificación de la actividad enzimática: significado para la regulación de flujos metabólicos Arch. Biol. Med. Exp.18, 331–358 (in Spanish)

J. M. Olavarría & M. L. Cárdenas (1985) Cooperative behavior in monomeric enzymes. Change from negative to positive cooperativity by effect of a ligand Arch. Biol. Med. Exp. 18, 285–292

D. Pollard-Knight, B. A. Connolly, A. Cornish-Bowden & I. P. Trayer (1985) Effect of glycerol on glucokinase activity: loss of co-operative behavior with respect to glucose Arch. Biochem. Biophys. 237, 328–334 [ Download PDF ]

1984

K. A. H. Adams, A. C. Storer & A. Cornish-Bowden (1984) Enzyme kinetics calculations: the direct linear plot procedure J. Chem. Educ. 61, 527 [ Download PDF ]

M. L. Cárdenas, E. Rabajille & H. Niemeyer (1984) Fructose a good substrate for rat-liver glucokinase (hexokinase D) Biochem. J. 222, 363–370 [ Download PDF ]

M. L. Cárdenas, E. Rabajille & H. Niemeyer (1984) Suppression of kinetic cooperativity of hexokinase D (glucokinase) by competitive inhibitors Eur. J. Biochem. 145, 163–171 [ Download PDF ]

A. Cornish-Bowden (1984) Enzyme specificity: its meaning in the general case J. Theor. Biol. 108, 451–457 [ Download PDF ]

A. Cornish-Bowden (1984) The prediction of repetitive protein sequences from amino acid compositions: a comment Biochem. J. 217, 340 [ Download PDF ]

A. Cornish-Bowden (1984) No introns in insect globin genes Nature 310, 724 [ Download PDF ]

A. Cornish-Bowden, M. Gregoriou & D. Pollard-Knight (1984) Rat-liver glucokinase as a mnemonical enzyme in Dynamics of Biochemical Systems (ed. J. Ricard & A. Cornish-Bowden), Plenum, New York

D. Pollard-Knight & A. Cornish-Bowden (1984) Solvent isotope effects on the glucokinase reaction: negative co-operativity and a large inverse isotope effect in 2H2O Eur. J. Biochem. 141, 157–163 [ Download PDF ]

A. Reyes & M. L. Cárdenas (1984) All hexokinase isoenzymes coexist in rat hepatocytes Biochem. J. 221, 303–309 [ Download PDF ]

A. Reyes, E. Rabajille, M. L. Cárdenas & H. Niemeyer (1984) Stability of hexokinases A, B, and C, and N-acetylglucosamine kinase in liver cells isolated from rats submitted to diabetes and several dietary conditions Biochem. J.221, 311–315 [ Download PDF ]

J. Ricard & A. Cornish-Bowden (1984) Dynamics of Biochemical Systems (Proceedings of a NATO Advanced Research Workshop held at Marseilles, France, 1983), Plenum Press, New York

M. L. Vera, M. L. Cárdenas & H. Niemeyer (1984) Kinetic, chromatographic and electrophoretic studies on glucose-phosphorylating enzymes of rat intestinal mucosa Arch. Biochem. Biophys. 229, 237–245 [ Download PDF ]

1983

A. Cornish-Bowden (1983) Relating proteins by amino acid composition Methods Enzymol. 91, 60–75 [ Download PDF ]

A. Cornish-Bowden (1983) Phenetic methods of classification use information that is disregarded by minimum-length methods J. Theor. Biol. 101, 317–319 [ Download PDF ]

A. Cornish-Bowden (1983) The amino acid compositions of proteins are correlated with their molecular sizes Biochem. J. 213, 271–274 [ Download PDF ]

A. Cornish-Bowden (1983) Metabolic efficiency: is it a useful concept? Biochem. Soc.Trans. 11, 44–45 [ Download PDF ]

M. Gregoriou, I. P. Trayer & A. Cornish-Bowden (1983) Isotope-exchange evidence that glucose 6-phosphate inhibits rat-muscle hexokinase II at an allosteric site Eur. J. Biochem. 134, 283–288 [ Download PDF ]

1982

R. Cammack, R. H. Jackson, A. Cornish-Bowden & J. A. Cole (1982) Electron spin resonance studies of the NADH-dependent nitrite reductase from Escherichia coli K12 Biochem. J. 207, 333–339 [ Download PDF ]

A. Cornish-Bowden (1982) Weighting of linear plots in enzyme kinetics J. Mol. Sci. 2, 107–112 [ Download PDF ]

A. Cornish-Bowden (1982) Related genes can have unrelated introns Nature 297, 625–626 [ Download PDF ]

R. H. Jackson, J. A. Cole & A. Cornish-Bowden (1982) The steady-state kinetics of the NADH-dependent nitrite reductase from Escherichia coli K12 Biochem. J. 203, 505–510 [ Download PDF ]

J. M. Olavarría, M. L. Cárdenas & H. Niemeyer (1982) Simulation of the kinetic cooperativity of glucokinase Arch. Biol. Med. Exp. 15, 365–369

D. Pollard-Knight & A. Cornish-Bowden (1982) Mechanism of liver glucokinase Mol. Cell. Biochem. 44, 71–80 [ Download PDF ]

D. Pollard-Knight, B. V. L. Potter, P. M. Cullis, G. Lowe & A. Cornish-Bowden (1982) The stereochemical course of phosphoryl transfer catalysed by glucokinase Biochem. J. 201, 421–423 [ Download PDF ]

1981

D. E. Briggs & A. Cornish-Bowden (1981) The calculation of results of α-amylase assays J. Inst. Brew. 87, 222–223 [ Download PDF ]

A. Cornish-Bowden (1981) Interpretation of amino acid compositions Trends Biochem. Sci. 6, 217–219 [ Download PDF ]

A. Cornish-Bowden (1981) Basic Mathematics for Biochemists, Chapman and Hall, London (137 pp.)

A. Cornish-Bowden (1981) Thermodynamic aspects of glycolysis Biochem. Educ. 9, 133–137 9, 133–137 [ Download PDF ]

A. Cornish-Bowden (1981) Robust estimation in enzyme kinetics pp. 105–120 in Design and Analysis of Enzyme and Pharmacokinetic Experiments (ed. L. Endrenyi), Plenum, New York [ Download PDF ]

A. Cornish-Bowden & L. Endrenyi (1981) Fitting of enzyme kinetic data without prior knowledge of weights Biochem. J. 193, 1005–1008 [ Download PDF ]

A. Cornish-Bowden & M. Gregoriou (1981) Measurement of flux ratios as a probe of enzyme kinetic mechanisms Trends Biochem. Sci. 6, 149–150 [ Download PDF ]

M. Gregoriou, A. Cornish-Bowden & I. P. Trayer (1981) Isotope-exchange evidence for allosteric regulation of hexokinase II by glucose 6-phosphate and for an obligatory addition of substrates Biochem. Soc. Trans. 9, 62–63 [ Download PDF ]

M. Gregoriou, I. P. Trayer & A. Cornish-Bowden (1981) Isotope exchange evidence for an ordered mechanism for rat-liver glucokinase, a monomeric co-operative enzyme Biochemistry 20, 499–506 [ Download PDF ]

R. H. Jackson, J. A. Cole & A. Cornish-Bowden (1981) The steady-state kinetics of the NADH-dependent nitrite reductase from Escherichia coli K12: nitrite and hydroxylamine reduction Biochem. J. 199, 171–178 [ Download PDF ]

R. H. Jackson, A. Cornish-Bowden & J. A. Cole (1981) Prosthetic groups of the NADH-dependent nitrite reductase from Escherichia coli K12 Biochem. J. 193, 861–867 [ Download PDF ]

1980

D. E. Briggs, A. Cornish-Bowden & M. T. Smith (1980) α-Amylase assays: calculation of results J. Inst. Brew. 86, 162–163 [ Download PDF ]

A. Cornish-Bowden (1980) Critical values for testing the significance of amino acid composition indexes Anal. Biochem. 105, 233–238 [ Download PDF ]

A. Cornish-Bowden (1980) The random character of protein evolution and its effect on the reliability of phylogenetic information deduced from amino acid sequences and compositions Biochem. J. 191, 349–354 [ Download PDF ]

A. Cornish-Bowden & J. T. Wong (1980) Validity of the jack-knife technique for analysing enzyme kinetic data Biochem. J. 185, 535–536 [ Download PDF ]

1979

M. L. Cárdenas, E. Rabajille & H. Niemeyer (1979) Kinetic cooperativity of glucokinase with glucose Arch. Biol. Med. Exp. 12, 571–580 [ Download PDF ]

A. Cornish-Bowden (1979) Fundamentals of Enzyme Kinetics, Butterworths, London & Boston (220 pp.)

A. Cornish-Bowden (1979) Validity of a steady-state treatment of inactivation kinetics Eur. J. Biochem. 93, 969–976 [ Download PDF ]

A. Cornish-Bowden (1979) How reliably do amino acid compositions predict sequence similarities between proteins? J. Theor. Biol. 76, 369–386 [ Download PDF ]

A. Cornish-Bowden, B. A. Connolly, M. Gregoriou, M. J. Holroyde, A. C. Storer & I. P. Trayer (1979) Mammalian hexokinases: a system for the study of co-operativity in monomeric enzymes Arch. Biol. Med. Exper. 12, 581–589 [ Download PDF ]

M. T. Smith, A. Cornish-Bowden & D. E. Briggs (1979) The determination of barley α-amylase activity J. Inst. Brew. 85, 157–159 [ Download PDF ]

1978

M. L. Cárdenas, E. Rabajille & H. Niemeyer (1978) Maintenance of the monomeric structure of glucokinase under reacting conditions Arch. Biochem. Biophys. 190, 142–148 [ Download PDF ]

K. J. Coleman, A. Cornish-Bowden & J. A. Cole (1978) Purification and properties of nitrite reductase from Escherichia coli K12 Biochem. J. 175, 483–493 [ Download PDF ]

K. J. Coleman, A. Cornish-Bowden & J. A. Cole (1978) Activation of nitrite reductase from Escherichia coli K12 by oxidized nicotinamide–adenine dinucleotide Biochem. J. 175, 495–499 [ Download PDF ]

K. J. Coleman, B. M. Newman, A. J. Cornish-Bowden & J. A. Cole (1978) Nitrite reduction by bacteria in Microbiology — 1978 (ed. D. Schlessinger), pp. 334–338, American Society of Microbiology, Washington, DC [ Download PDF ]

A. Cornish-Bowden (1978) Amino acid compositions provide a reliable guide to sequence similarities Biochem. Soc. Trans. 6, 727–728 [ Download PDF ]

A. Cornish-Bowden (1978) Interpretation of the difference index as a guide to protein sequence similarity J. Theor. Biol. 74, 155–161 [ Download PDF ]

A. Cornish-Bowden & R. Eisenthal (1978) Estimation of Michaelis constant and maximum velocity from the direct linear plot Biochim. Biophys. Acta 523, 268–272 [ Download PDF ]

A. Cornish-Bowden, W. R. Porter & W. F. Trager (1978) Evaluation of distribution-free confidence limits for enzyme kinetic parameters J. Theor. Biol. 74, 163–175 [ Download PDF ]

A. Cornish-Bowden & J. T. Wong (1978) Evaluation of rate constants for enzyme-catalysed reactions by the jackknife technique: application to liver alcohol dehydrogenase Biochem. J. 175, 969–976 [ Download PDF ]

1977

A. Cornish-Bowden (1977) An automatic method for deriving steady-state rate equations Biochem. J. 165, 55–59 [ Download PDF ]

A. Cornish-Bowden (1977) Assessment of protein sequence identity from amino acid composition data J. Theor. Biol. 65, 735–742 [ Download PDF ]

A. Cornish-Bowden & A. Marson (1977) Evaluation of the non-randomness of protein compositions J. Mol. Evol. 10, 231–240 [ Download PDF ]

A. C. Storer & A. Cornish-Bowden (1977) Kinetic evidence for a mnemonical mechanism for rat liver glucokinase Biochem. J. 165, 61–69 [ Download PDF ]

R. N. F. Thorneley & A. Cornish-Bowden (1977) Kinetics of nitrogenase of Klebsiella pneumoniae: heterotropic interactions between magnesium-adenosine 5′-diphosphate and magnesium-adenosine 5′-triphosphate Biochem. J. 165, 255–262 [ Download PDF ]

1976

K. Brocklehurst & A. Cornish-Bowden (1976) The pre-eminence of kcat in the manifestation of optimal enzyme activity delineated by using the Briggs–Haldane two-step irreversible kinetic model Biochem. J. [ Download PDF ]

A. Cornish-Bowden (1976) Estimation of the dissociation constants of enzyme–substrate complexes from steady-state measurements Biochem. J. 153, 455–461 [ Download PDF ]

A. Cornish-Bowden (1976) Principles of Enzyme Kinetics, Butterworths, London (206 pp.)

A. Cornish-Bowden (1976) Algebraic methods for deriving steady-state rate equation: practical difficulties with mechanisms that contain repeated rate constants Biochem. J. 159, 167 [ Download PDF ]

A. Cornish-Bowden (1976) The effect of natural selection on enzymic catalysis J. Mol. Biol. 101, 1–9 [ Download PDF ]

M. J. Holroyde, M. B. Allen, A. C. Storer, A. S. Warsy, J. M. E. Chesher, I. P. Trayer, A. Cornish-Bowden & D. G. Walker (1976) The purification in high yield of rat hepatic glucokinase Biochem. J. 153, 363–373 [ Download PDF ]

M. Markus, B. Hess, J. H. Ottaway & A. Cornish-Bowden (1976) The analysis of kinetic data in biochemistry: a critical review of methods FEBS Lett. 63, 225–230 [ Download PDF ]

A. C. Storer & A. Cornish-Bowden (1976) Concentration of MgATP2– and other ions in solution Biochem. J. 159, 1–5 [ Download PDF ]

A. C. Storer & A. Cornish-Bowden (1976) Kinetics of rat-liver glucokinase: co-operative interactions with glucose at physiologically significant concentrations Biochem. J. 159, 7–14 [ Download PDF ]

1975

A. Cornish-Bowden (1975) The physiological significance of negative co-operativity J. Theor. Biol. 51, 233–235 [ Download PDF ]

A. Cornish-Bowden (1975) The use of the direct linear plot for determining initial velocities Biochem. J. 149, 305–312 [ Download PDF ]

A. Cornish-Bowden & D. E. Koshland, Jr. (1975) Diagnostic uses of Hill (logit and Nernst) plots J. Mol. Biol. 95, 201–212 [ Download PDF ]

G. P. Margison, P. J. O’Connor & A. Cornish-Bowden (1975) Role of apurinic sites in the resistance of methylated oligodeoxyribonucleotides to degradation by spleen exonuclease Biochem. J. 151, 249–256 [ Download PDF ]

H. Niemeyer, M. L. Cárdenas, E. Rabajille, T. Ureta, L. Clark-Turri, & J. Peñaranda, J. (1975) Sigmoidal kinetics of glucokinase Enzyme 20, 321–333 [ Download PDF ]

A. C. Storer, M. G. Darlison & A. Cornish-Bowden (1975) The nature of experimental error in enzyme kinetic measurements Biochem. J. 151, 361–367 [ Download PDF ]

1974

A. Cornish-Bowden (1974) A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors Biochem. J. 137, 143–144 [ Download PDF ]

A. Cornish-Bowden & R. Eisenthal (1974) Statistical considerations in the estimation of enzyme kinetic parameters by the direct linear plot and other methods Biochem. J. 139, 721–730 [ Download PDF ]

R. Eisenthal & A. Cornish-Bowden (1974) The direct linear plot Biochem. J. 139, 715–720 ; among the 0.05% most cited papers in this journal] [ Download PDF ]

A. C. Storer & A. Cornish-Bowden (1974) The kinetics of coupled enzyme reactions Biochem. J. 141, 205–209 [ Download PDF ]

C. W. Wharton, A. Cornish-Bowden, K. Brocklehurst & E. M. Crook (1974) Kinetics of the hydrolysis of N-benzoyl-L-serine methyl ester catalysed by bromelain and by papain Biochem. J. 141, 365–381 [ Download PDF ]

1972

A. J. Cornish-Bowden (1972) Analysis of progress curves in enzyme kinetics Biochem. J. 130, 637–639 [ Download PDF ]

1971

A. J. Cornish-Bowden & D. E. Koshland, Jr. (1971) The quaternary structure of proteins composed of identical subunits J. Biol. Chem. 246, 3092–3102 [ Download PDF ]

1970

A. Cornish-Bowden & D. E. Koshland, Jr. (1970) A general method for the quantitative determination of saturation curves Biochemistry 9, 3325–3336 [ Download PDF ]

A. Cornish-Bowden & D. E. Koshland, Jr. (1970) The influence of binding domains on the nature of subunit interactions in oligomeric proteins J. Biol. Chem. 245, 6241–6250 [ Download PDF ]

A. J. Cornish-Bowden, R. A. Cook & D. E. Koshland, Jr. (1970) A curve-fitting procedure for the study of the binding of small molecules to multisubunit proteins Il Farmaco 25, 786–798 [ Download PDF ]

J. R. Knowles, R. S. Bayliss, A. J. Cornish-Bowden, P. Greenwell, T. M. Kitson, H. C. Sharp & G. B. Wybrandt (1970) Towards a mechanism for pepsin pp. 237–250 in Structure-Function Relationships of Proteolytic Enzymes (ed. P. Desnuelle, H. Neurath & M. Ottesen), Munksgaard, Copenhagen [ Download PDF ]

D. E. Koshland, Jr., R. A. Cook & A. Cornish-Bowden (1970) Co-operative phenomena in yeast glyceraldehyde 3-phosphate dehydrogenase pp. 199–208 in Pyridine Nucleotide-Dependent Dehydrogenases (ed. H. Sund), Springer–Verlag, Berlin [ Download PDF ]

1969

A. J. Cornish-Bowden, P. Greenwell & J. R. Knowles (1969) The rate limiting step in pepsin-catalysed reactions and evidence against an acyl-enzyme intermediate Biochem. J. 113, 369–375 [ Download PDF ]

A. J. Cornish-Bowden & J. R. Knowles (1969) The pH-dependence of pepsin-catalysed reactions Biochem. J. 113, 353–362 [ Download PDF ]